I used to be very uncomfortable with pairing prints. It can seem like doing too much at once. Truthfully, when not worn right, it IS too much at once. For instance, polka dots and stripes combined. Very uncomfortable look for the eyes. Smart advice from some designer (Rachel Ray, I think): you should only pair prints that are related. For instance, a top that has white and blue horizontal stripes with a skirt that has white and red horizontal stripes.
You can do lots with non-stripes too. See Camille Rowe in this photograph by Tommy Ton. It was displayed in Harper's Bazaar's Garden Party, December 2013.